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Purified Rat Anti-Mouse GPVI Monoclonal Antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
M011-0
Purified Rat Anti-Mouse GPVI Monoclonal Antibody
德国emfret 0.1 mg 有货
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产品特性        

Product Cat#: M011-0
Product type: Primary antibody
Antigen: GPVI
Immunogen: Recombinant protein
Species immunized: Rat
Isotype: IgG2a
Applications: This preparation can be used for immunoprecipitation, immunohistochemical analysis of acetone-fixed frozen sections, and immunofluorescent staining (1-3 µg/106 platelets or cells). JAQ1 recognizes mouse GPVI in a Western blot analysis under non-reducing condtions.
Reactivity: Mouse
Clonality (clone number): Monoclonal, JAQ1
Form: Liquid
Buffer: 0.1 mg purified immunoglobulin in 20 mM Tris buffered saline containing 0.25% BSA and 0.09% (w/v) sodium azide.
Concentration: 0.5 mg/mL
Purity: Protein G affinity purified.
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: -
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靶标信息

The JAQ1 antibody reacts with mouse GPVI, a platelet/megakaryocyte-specific 60 to 65 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily1. GPVI noncovalently associates with the signal-transducing FcR-chain in the platelet membrane and serves as an activating collagen receptor2. JAQ1 inhibits collagen-induced aggregation of mouse platelets. JAQ1 alone does not activate platelets. Cross-linking of JAQ1 by a secondary antibody, however, induces activation and aggregation of mouse platelets

产品来源

洱畔科技实验室