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Mouse ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA kit

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
EK-07-1114
Mouse ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA kit
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: EK-07-1114
Product name: Mouse ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA kit
Target Name: ABCB1
Species Reactivity: Mouse
Product Size: 48/96 Tests
Sensitivity: 0.07 ng/ml
Assay range: 0.5-10 ng/ml
Assay Time: 90 minutes
Platform: Colorimetric Microplate Reader
Conjugate: HRP
ELISA Type: Competitive ELISA
Detection Method: Colorimetric
Storage temperature: Store at 2-8°C
Stability: Stable within the expiration date under suggested storage conditions
Shipping condition: Wet ice
Kit Contents: Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials),
Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial),
Balance solution (1 vial), Instruction (1 copy)
Other Names of Target: CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin sensitivity
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靶标信息

P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.

产品来源

洱畔科技实验室

文件下载

MSDS-EK-07-1114.pdf (下载157 )