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Mouse AT Rich Interactive Domain Containing Protein 1B ELISA Kit

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
EK-07-1057
Mouse AT Rich Interactive Domain Containing Protein 1B ELISA Kit
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: EK-07-1057
Product name: Mouse AT Rich Interactive Domain Containing Protein 1B ELISA Kit
Target Name: ARID1B
Species Reactivity: Mouse
Product Size: 48/96 Tests
Sensitivity: 0.49 ng/ml
Assay range: 5.0-100 ng/ml
Assay Time: 90 minutes
Platform: Colorimetric Microplate Reader
Conjugate: HRP
ELISA Type: Competitive ELISA
Detection Method: Colorimetric
Storage temperature: Store at 2-8°C
Stability: Stable within the expiration date under suggested storage conditions
Shipping condition: Wet ice
Kit Contents: Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials),
Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial),
Balance solution (1 vial), Instruction (1 copy)
Other Names of Target: ARID 1B;BAF 250b; BAF250b; BRG1 associated factor 250b
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靶标信息

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. Binds DNA non-specifically.

产品来源

洱畔科技实验室

文件下载

MSDS-EK-07-1057.pdf (下载162 )