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Human Matrix Metalloproteinsae 1 ELISA kit

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
EK-07-0221
Human Matrix Metalloproteinsae 1 ELISA kit
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: EK-07-0221
Product name: Human Matrix Metalloproteinsae 1 ELISA kit
Target Name: MMP 1
Species Reactivity: Human
Product Size: 48/96 Tests
Sensitivity: 0.13 ng/mL
Assay range: 2.5-50 ng/mL
Assay Time: 90 minutes
Platform: Colorimetric Microplate Reader
Conjugate: HRP
ELISA Type: Competitive ELISA
Detection Method: Colorimetric
Storage temperature: Store at 2-8°C
Stability: Stable within the expiration date under suggested storage conditions
Shipping condition: Wet ice
Kit Contents: Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ),
Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ),
Balance solution ( 1 vial ), Instruction ( 1 copy )
Other Names of Target: CLGN; CLG; Collagenase, Fibroblast; Fibroblast Collagenase; Interstitial Collagenase; Matrix Metallopeptidase 1 (interstitial collagenase); Matrix Metalloprotease 1; OTTHUMP00000045866
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靶标信息

The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer’s, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.

产品来源

洱畔科技实验室

文件下载

MSDS-EK-07-0221.pdf (下载150 )