Human Cyclic Adenosine Monophosphate ELISA Kit
产品特性
| Product Cat#: | EK-07-0162 |
| Product name: | Human Cyclic Adenosine Monophosphate ELISA Kit |
| Target Name: | cAMP |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 8.8 pmoL/mL |
| Assay range: | 50-1000 pmoL/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | cyclic AMP, or 3',5'-cyclic adenosine monophosphate |
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靶标信息
Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.
产品来源
洱畔科技实验室
