Human Complement Component 3 ELISA kit
产品特性
| Product Cat#: | EK-07-0265 |
| Product name: | Human Complement Component 3 ELISA kit |
| Target Name: | C3 |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.15 µg/mL |
| Assay range: | 1.0-25 mg/L |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ), |
| Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ), | |
| Balance solution ( 1 vial ), Instruction ( 1 copy ) | |
| Other Names of Target: | Acylation-stimulating Protein Cleavage Product; AHUS5; ARMD9; ASP; C3 and PZP-like Alpha-2-macroglobulin Domain-containing Protein 1 Antibody C3 Antibody C3a Anaphylatoxin; CO3_HUMAN; Complement C3 Alpha Chain; Complement C3; Complement C3 Beta Chain; Complement C3 precursor; Complement C3b Alpha Chain; Complement C3c Alpha'Chain Fragment 2; Complement C3c Fragment; Complement C3d fragment; Complement C3f fragment; Complement C3g Fragment; Complement Component 3; Complement Component 3 Precursor; Complement Component C3; Complement Factor 3; CPAMD1; Plp |
靶标信息
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation.Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 .
产品来源
洱畔科技实验室
