DRD2/Dopamine D2 Receptor 抗体 (B-10): sc-5303
产品特性
| Product Cat#: | sc-5303 |
| Product type: | Primary antibody |
| Antigen: | D2DR/Dopamine D2 Receptor |
| Immunogen: | D2DR (B-10) is a mouse monoclonal antibody raised against amino acids 1-50 of dopamine receptor type 2 (D2DR) of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | WB, IP, IF, IHC(P), ELISA |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monclonal, B-10 |
| Form: | Liquid |
| Buffer: | Each vial contains 200 µg IgG2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
| Concentration: | 200 µg/ml |
| Purity: | Protein G purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: |
靶标信息
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:21645528).
Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
相关文献
1、PMID: 37266125 | Dopamine and serotonin alterations by Hizikia fusiformis extracts under in vitro cortical primary neuronal cell cultures. | Jung, JW. et al. 2023. Nutr Res Pract. 17: 408-420.
2、PMID: 36972629 | Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5. | Jeon, HM. et al. 2023. Neoplasia. 39: 100894.
3、PMID: 37482042 | The shape of our gut: Dissecting its impact on drug absorption in a 3D bioprinted intestinal model. | Macedo, MH. et al. 2023. Biomater Adv. 153: 213564.
4、PMID: 36656755 | Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue. | Zwang, TJ. et al. 2023. Elife. 12:
5、PMID: 36523297 | DRD1 and DRD4 are differentially expressed in breast tumors and breast cancer stem cells: pharmacological implications. | Rosas-Cruz, A. et al. 2022. Transl Cancer Res. 11: 3941-3950.
