C3 抗体 (B-9): sc-28294
产品特性
| Product Cat#: | sc-28294 |
| Product type: | Primary antibody |
| Antigen: | C3 |
| Immunogen: | C3 (B-9) is a mouse monoclonal antibody raised against amino acids 541-840 of C3 precursor of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | WB, IP, IF, IHC(P), ELISA |
| Reactivity: | 检测mouse, rat 和human 来源的 C3 precursor, C3a anaphylatoxin, C3 α chain, C3 β chain and C3b α′ chain |
| Clonality (clone number): | Monoclonal, B-9 |
| Form: | Liquid |
| Buffer: | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
| Concentration: | 0.2 mg/ml |
| Purity: | Protein A purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Acylation stimulating protein cleavage product antibody |
| AHUS5 antibody | |
| ARMD9 antibody | |
| ASP antibody | |
| C3 and PZP like alpha 2 macroglobulin domain containing protein 1 antibody | |
| C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody | |
| C3 antibody | |
| c3 complement antibody | |
| C3adesArg antibody | |
| CO3_HUMAN antibody | |
| Complement C3 alpha chain antibody | |
| Complement C3 antibody | |
| Complement C3b alpha' chain antibody | |
| Complement C3c alpha' chain fragment 1 antibody | |
| Complement C3c alpha' chain fragment 2 antibody | |
| Complement C3c alpha" chain fragment 2 antibody | |
| Complement C3d fragment antibody | |
| Complement C3dg fragment antibody | |
| Complement C3f fragment antibody | |
| Complement C3g fragment antibody | |
| Complement component 3 antibody | |
| Complement factor 3 antibody | |
| CPAMD1 antibody | |
| HEL S 62p antibody | |
| omplement C3 beta chain antibody |
靶标信息
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity).
It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
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