Anti-ZBTB48 antibody
产品特性
| Product Cat#: | AB-06-4687 | |||||||||||||||||
| Product type: | Primary antibody | |||||||||||||||||
| Antigen: | ZBTB48 | |||||||||||||||||
| Immunogen: | Peptide | |||||||||||||||||
| Species immunized: | Rabbit | |||||||||||||||||
| Isotype: | IgG | |||||||||||||||||
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:200); Immunocytochemistry (1:50-1:200) | |||||||||||||||||
| Reactivity: | Human, Mouse, Rat | |||||||||||||||||
| Clonality (clone number): | Polyclonal | |||||||||||||||||
| Form: | Liquid | |||||||||||||||||
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. | |||||||||||||||||
| Concentration: | 1 mg/ml | |||||||||||||||||
| Purity: | Peptide affinity purified | |||||||||||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | |||||||||||||||||
| Alternative names: | 0610011D15Rik antibody | AI327031 antibody | GLI Kruppel family member HKR3 antibody | HKR3 antibody | Krueppel related zinc finger protein 3 antibody | Krueppel-related zinc finger protein 3 antibody | OTTMUSP00000031803 antibody | pp9964 antibody | Protein HKR3 antibody | RP23-445E20.3 antibody | ZBT48_HUMAN antibody | ZBTB 48 antibody | Zbtb48 antibody | Zinc finger and BTB domain containing 48 antibody | Zinc finger and BTB domain containing protein 48 antibody | Zinc finger and BTB domain-containing protein 48 antibody | Zinc finger protein 855 antibody | ZNF855 antibody |
靶标信息
Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5′-TTAGGG-3′ repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).
产品来源
洱畔科技实验室