Anti-XRCC4 antibody
产品特性
| Product cat: | AB-06-4672 |
| Product type: | Primary antibody |
| Antigen: | XRCC4 |
| Immunogen: | KLH conjugated synthetic peptide derived from human XRCC4 151-260/336 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:2400) |
| Reactivity: | Mouse,Dog, Pig, Cow, Horse, Rabbit, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol,0.03% Proclin300, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DNA double strand break repair and V(D)J recombination protein XRCC4 |
| DNA double-strand break repair and V(D)J recombination protein XRCC4 | |
| DNA repair protein XRCC4 | |
| DNA-repair protein XRCC4 | |
| X ray repair complementing defective repair in Chinese hamster cells 4 | |
| X ray repair cross complementing protein 4 | |
| X-ray repair complementing defective repair in Chinese hamster cells 4 | |
| X-ray repair cross-complementing protein 4 | |
| XRCC 4 | |
| XRCC-4 |
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靶标信息
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
产品来源
洱畔科技实验室