Anti-WNT1 antibody
Specifications
| Product Cat#: | AB-07-2233 |
| Product type: | Primary antibody |
| Antigen: | WNT1 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from Internal of human WNT1. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500); ELISA (1:15000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ONCOGENE INT1, wingless-type MMTV integration site family, member 1, INT1, Proto-oncogene protein Wnt-1 [Precursor] |
展开
靶标信息
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity). In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (PubMed:15454084, PubMed:16116452). Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (PubMed:2202907, PubMed:16116452). Has a role in osteoblast function, bone development and bone homeostasis (By similarity).
产品来源
洱畔科技实验室
