Anti-WASL antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | WASL |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry(1:40-1:200); Immunocytochemistry (1:40-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (JU07-31) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | WASP family, verprolin homology domain-containing protein 1 antibody |
| WASP family member 1 antibody | |
| FLJ31482 antibody | |
| Homology of dictyostelium scar 1 antibody | |
| KIAA0269 antibody | |
| Protein WAVE-1 antibodyv Protein WAVE1 antibody | |
| Scar, Dictyostelium, homology of, 1 antibody | |
| SCAR1 antibody | |
| Similar to a plant extensin like protein antibody | |
| Verprolin homology domain containing protein 1 antibody | |
| Verprolin homology domain-containing protein 1 antibody | |
| WAS protein family, member 1 antibody | |
| Wasf1 antibody | |
| WASF1_HUMAN antibody | |
| WASL antibody | |
| WASP family 1 antibody | |
| WASP family protein member 1 antibody | |
| WASP family, verprolin homology domain-containing protein antibody | |
| WAVE antibody | |
| WAVE1 antibody | |
| Wiskott Aldrich syndrome protein family member 1 antibody | |
| Wiskott-Aldrich syndrome protein family member 1 antibody |
靶标信息
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex . Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization . Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia . In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization . Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linea.
产品来源
洱畔科技实验室
