Anti-VE Cadherin Recombinant Rabbit Monoclonal antibody
产品特性
| Product Cat#: | AB-06-5100 |
| Product type: | Primary antibody |
| Antigen: | VE Cadherin |
| Immunogen: | Synthetic peptide within human VECadherin aa 1-650. |
| Molecular weight: | Predicted band size: 88 kDa, Observed band size: 120/140 kDa |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunocytochemistry/Immunofluorescence (1:50-1:100); Flow Cytometry (1:500-1:1000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, PSH03-15 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 40% glycerol, 0.05% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 7B 4 antibody |
| 7B4 antibody | |
| 7B4 antigen antibody | |
| CADH5_HUMAN antibody | |
| Cadherin 5 antibody | |
| Cadherin 5 type 2 antibody | |
| Cadherin 5, type 2 (vascular endothelium) antibody | |
| Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody | |
| cadherin, vascular endothelial antibody | |
| cadherin, vascular endothelial, 1 antibody | |
| Cadherin-5 antibody | |
| Cadherin5 antibody | |
| CD 144 antibody | |
| CD144 antibody | |
| CD144 antigen antibody | |
| CDH 5 antibody | |
| CDH5 antibody | |
| CDH5 protein antibody | |
| Endothelial specific cadherin antibody | |
| FLJ17376 antibody | |
| OTTHUMP00000174777 antibody | |
| Vascular endothelial cadherin antibody | |
| Vascular epithelium cadherin antibody | |
| VE Cad antibody | |
| VE-cadherin antibody | |
| VEC antibody |
靶标信息
Cadherins are calcium-dependent cell adhesion proteins (By similarity).
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (PubMed:21269602).
This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity).
It associates with alpha-catenin forming a link to the cytoskeleton (PubMed:10861224).
Acts in concert with KRIT1 and PALS1 to establish and maintain correct endothelial cell polarity and vascular lumen (By similarity).
These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (PubMed:20332120).
Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (PubMed:20332120).
产品来源
洱畔科技实验室
