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Anti-SLC22A1 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-4086
Anti-SLC22A1 antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-4086
Product type: Primary antibody
Antigen: SLC22A1
Immunogen: KLH conjugated synthetic peptide derived from human SLC22A1 51-150/554
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot ( 1:800-1:2000 )
Reactivity: Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer ( pH7.4 ), 1 % BSA, 50 % glycerol, 0.05 % NaN3, 0.03 % Proclin300.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: hOCT1
OCT1
oct1_cds
Organic Cation tTransporter 1
S22A1_HUMAN
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靶标信息

Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-4086.pdf (下载132)