Anti-SKA3 Mouse Monoclonal antibody
产品特性
| Product Cat#: | AB-06-4075 |
| Product type: | Primary antibody |
| Antigen: | SKA3 |
| Immunogen: | Amino acids 154-166 within an internal region of Ska3 of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot ( 1:100-1:1000 ); Immunoprecipitation ( 1-3 μg per 100-500 μg of total protein ( 1 ml of cell lysate ) ); Immunofluorescence ( 1:50-1:400 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal ( 4G1 ) |
| Form: | Liquid |
| Buffer: | 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | C13orf3 Antibody |
| RAMA1 Antibody | |
| SKA3 Antibody | |
| SKA3_HUMAN Antibody | |
| Spindle and Kinetochore Associated Complex Subunit 3 Antibody | |
| Spindle and Kinetochore-associated Protein 3 Antibody |
靶标信息
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
产品来源
洱畔科技实验室