购物车里没有产品。

Anti-Septin 2 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-4007
Anti-Septin 2 antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-4007
Product type: Primary antibody
Antigen: Septin 2
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Immunoprecipitation; Immunofluorescence; Western Blot (1:600-1:1000); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:60-1:200); Flow Cytometry (1:40-1:100)
Reactivity: Mouse, Rat and Human
Clonality (clone number): Monoclonal (JB41-30)
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: DIFF6 antibody
HNEDD5 antibody
KIAA0158 antibody
NEDD 5 antibody
NEDD5 antibody
Neural precursor cell expressed developmentally down regulated 5 antibody
Neural precursor cell expressed developmentally down regulated protein 5 antibody
Pnutl3 antibody
Protein NEDD5 antibody
SEPT2 antibody
展开

靶标信息

Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-4007.pdf (下载158 )