Anti-SENP2 antibody
产品特性
| Product Cat#: | AB-06-4005 |
| Product type: | Primary antibody |
| Antigen: | SENP2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human SENP2 1-100/589 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2000) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4),1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Axam2 |
| DKFZp762A2316 | |
| KIAA1331 | |
| Senp2 | |
| SERP2 | |
| SENP2_HUMAN | |
| Sentrin specific protease 2 | |
| Sentrin-specific protease 2 | |
| Sentrin/SUMO specific protease SENP2 | |
| Sentrin/SUMO-specific protease SENP2 | |
| SMT3 specific isopeptidase 2 | |
| SMT3-specific isopeptidase 2 | |
| Smt3ip2 |
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靶标信息
Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).
产品来源
洱畔科技实验室
