Anti-SAMD8 antibody
Specifications
| Product Cat#: | AB-06-3958 |
| Product type: | Primary antibody |
| Antigen: | SAMD8 |
| Immunogen: | KLH conjugated synthetic peptide derived from human SAMD8 81-180/415 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | 1110053F04Rik |
| 1700010P07Rik | |
| FLJ25082 | |
| MGC118303 | |
| RP11-487I5.5 | |
| SMSr | |
| Sphingomyelin synthase related | |
| Sphingomyelin synthase related protein 1 |
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靶标信息
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.
产品来源
洱畔科技实验室
