Anti-RPS19BP1 antibody
产品特性
| Product Cat#: | AB-08-0158 |
| Product type: | Primary antibody |
| Antigen: | RPS19BP1 |
| Immunogen: | Recombinant protein within human RPS19BP1 aa 1-136. |
| Molecular weight: | Predicted band size: 15 kDa, Observed band size: 20 kDa |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunocytochemistry/Immunofluorescence (1:50 – 1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 40% glycerol, 0.1% BSA, 0.05% NaN3. |
| Concentration: | - mg/mL |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Active regulator of SIRT1; 40S ribosomal protein S19-binding protein 1 (RPS19-binding protein 1; S19BP); RPS19BP1; AROS |
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靶标信息
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1 (PubMed:34516797).
Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity (PubMed:17964266).
产品来源
洱畔科技实验室
