Anti-RAR Beta antibody
Specifications
| Product Cat#: | AB-06-3824 |
| Product type: | Primary antibody |
| Antigen: | RAR Beta |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Retinoic acid R-beta |
| HAP | |
| HBV activated protein | |
| HBV-activated protein | |
| Hepatitis B virus activated protein | |
| NR1B2 | |
| Nuclear receptor subfamily 1 group B member 2 | |
| RAR B | |
| RAR beta | |
| RAR epsilon | |
| RARB | |
| Retinoic acid receptor beta 2 | |
| Retinoic acid receptor beta 4 | |
| Retinoic acid receptor beta 5 | |
| Retinoic acid receptor beta | |
| Retinoic acid receptor beta polypeptide | |
| RRB 2 | |
| RARB_HUMAN |
靶标信息
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5′-AGGTCA-3′ sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed:12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed:29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
产品来源
洱畔科技实验室
