Anti-RAPGEF3 antibody
产品特性
| Product Cat#: | AB-07-3585 |
| Product type: | Primary antibody |
| Antigen: | RAPGEF3 |
| Immunogen: | A synthetic peptide derived from human RAPGEF3. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:40000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CAMP-regulated guanine nucleotide exchange factor I; CAMP-GEFI; Exchange factor directly activated by cAMP 1; Epac 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP |
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靶标信息
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
产品来源
洱畔科技实验室
