Anti-RAD51D antibody
产品特性
| Product Cat#: | AB-06-3807 |
| Product type: | Primary antibody |
| Antigen: | RAD51D |
| Immunogen: | KLH conjugated synthetic peptide derived from human RAD51D 1-100/328 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | BROVCA4 |
| DNA repair protein RAD51 homolog 4 | |
| HsTRAD | |
| OTTHUMP00000163851 | |
| OTTHUMP00000163852 | |
| OTTHUMP00000163853 | |
| R51H3 | |
| RA51D_HUMAN | |
| RAD51 homolog D (S. cerevisiae) | |
| RAD51 homolog D | |
| RAD51 like 3 (S. cerevisiae) | |
| RAD51 paralog D | |
| RAD51, S. cerevisiae, homolog of, D | |
| RAD51-like protein 3 | |
| Rad51l3 | |
| Recombination repair protein | |
| S. cerevisiae RAD51-like 3 |
靶标信息
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
产品来源
洱畔科技实验室
