Anti-RAB11-FIP2 antibody
Specifications
| Product Cat#: | AB-06-3780 |
| Product type: | Primary antibody |
| Antigen: | RAB11-FIP2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human RAB11-FIP2 331-430/512 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | RAB11FIP2 |
| KIAA0941 | |
| NRip11 | |
| RAB11 Family Interacting Protein 2 (class I) | |
| Rab11 Family-Interacting Protein 2 | |
| RAB11 FIP2 Long Isoform | |
| Rab11-FIP2 | |
| RFIP2 |
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靶标信息
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.
产品来源
洱畔科技实验室
