Anti-PSAP antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PSAP |
| Immunogen: | Purified recombinant fragment of human PSAP expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:60-1:200); Flow Cytometry (1:60-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (F4-D5) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A1 activator antibody |
| Cerebroside sulfate activator antibody | |
| Co-beta-glucosidase antibody | |
| Component C antibody | |
| CSAct antibody | |
| Dispersin antibody | |
| GLBA antibody | |
| Glucosylceramidase activator antibody | |
| Proactivator polypeptide antibody | |
| Proactivator polypeptide precursor antibody | |
| Prosaposin (sphingolipid activator protein 1) antibody | |
| prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) antibody | |
| Prosaposin antibody | |
| Protein A antibody | |
| Protein C antibody | |
| PSAP antibody | |
| SAP-1 antibody | |
| SAP-2 antibody | |
| SAP_HUMAN antibody | |
| SAP1 antibody | |
| Saposin A antibody | |
| Saposin B antibody | |
| Saposin B Val antibody | |
| Saposin C antibody | |
| Saposin D antibody | |
| Saposin-D antibody | |
| Saposins antibody | |
| Sgp1 antibody | |
| Sphingolipid activator protein 1 antibody | |
| Sphingolipid activator protein 2 antibody | |
| Sulfated glycoprotein 1 antibody |
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靶标信息
Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.
Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.
Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).
Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.By similarity1 Publication
Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
产品来源
洱畔科技实验室
