Anti-PPP2R4 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PPP2R4 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:80-1:500); Immunocytochemistry (1:80-1:500); Flow Cytometry (1:80-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (G4-D9) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4),1%BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | subunit B antibody |
| KIAA0044 antibody | |
| MGC2184 antibody | |
| Phosphotyrosyl phosphatase activator antibody | |
| PP2A antibody | |
| PP2A phosphatase activator antibody | |
| PP2A subunit B antibody | |
| PP2A subunit B isoform PR53 antibody | |
| PP2A subunit B PR53 isoform antibody | |
| PPP2R4 antibody | |
| PR53 antibody | |
| PR53 isoform antibody | |
| Protein phosphatase 2, regulatory subunit B-prime antibody | |
| Protein phosphatase 2A activator regulatory subunit 4 antibody | |
| Protein phosphatase 2A regulatory subunit B' (PR 53) antibody | |
| PTPA antibody | |
| PTPA_HUMAN antibody | |
| Serine/threonine protein phosphatase 2A regulatory subunit B antibody | |
| Serine/threonine-protein phosphatase 2A activator antibody | |
| Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody | |
| Serine/threonine-protein phosphatase 2A regulatory subunit B antibody |
靶标信息
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+ (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg2+ (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
产品来源
洱畔科技实验室
