Anti-PPP1CB antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PPP1CB |
| Immunogen: | Recombinant protein corresponding to human PPP1CB aa 100-327. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:2000-1:10000); Immunoprecipitation(1:50); Immunohistochemistry (1:60-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JE45-08) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4),1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | MGC3672 antibody |
| PP 1B antibody | |
| PP-1B antibody | |
| PP1B antibody | |
| PP1B_HUMAN antibody | |
| PP1beta antibody | |
| PPP1CB antibody | |
| PPP1CD antibody | |
| Protein phosphatase 1 beta antibody | |
| Protein phosphatase 1 catalytic subunit beta isoform antibody | |
| Protein phosphatase 1 delta antibody | |
| Protein phosphatase 1, catalytic subunit, beta isozyme antibody | |
| Protein phosphatase 1, catalytic subunit, delta isoform antibody | |
| Serine threonine protein phosphatase PP1 beta catalytic subunit antibody | |
| Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody |
靶标信息
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the ‘Ser-418’ residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
产品来源
洱畔科技实验室
