Anti-Podoplanin antibody
产品特性
| Product Cat#: | AB-06-3636 |
| Product type: | Primary antibody |
| Antigen: | Podoplanin |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse Podoplanin 91-166/166 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Podoplanin /gp36 |
| Podoplanin Protein | |
| AGGRUS | |
| GLYCOPROTEIN 36 KD | |
| Podoplanin | |
| Glycoprotein 36 | |
| gp 36 | |
| GP 38 | |
| GP 40 | |
| gp36 | |
| GP38 | |
| GP40 | |
| HT1A 1 | |
| HT1A1 | |
| hT1alpha1 | |
| hT1alpha2 | |
| Lung type I Cell Membrane Associated Glycoprotein | |
| Lung type I Cell Membrane Associated Glycoprotein Isoform a | |
| Lung type I Cell Membrane Associated Glycoprotein T1A 2 | |
| OTS 8 | |
| OTS8 | |
| OTTHUMP00000009640 | |
| OTTHUMP00000044504 | |
| PA2.26 | |
| PA2.26 Antigen | |
| PDPN | |
| Podoplanin | |
| T1 Alpha | |
| T1 ALPHA GENE | |
| T1A | |
| TIA 2 |
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靶标信息
Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation (PubMed:14522983, PubMed:15231832, PubMed:17616532, PubMed:18215137, PubMed:17222411). Interaction with CD9, on the contrary, attenuates platelet aggregation induced by PDPN (PubMed:18541721). Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness (PubMed:17046996, PubMed:21376833).
产品来源
洱畔科技实验室
