Anti-Phospho-Tau (S396) antibody
产品特性
| Product Cat#: | AB-06-3564 |
| Product type: | Primary antibody |
| Antigen: | Phospho-Tau (S396) |
| Immunogen: | Synthetic phospho-peptide corresponding to residues surrounding Ser396 of human Tau |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:50-1:200); Immunofluorescence; Immunocytochemistry (1:100-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SN62-09) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AI413597 antibody |
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| Microtubule-associated protein tau antibody | |
| MSTD antibody | |
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| MTBT2 antibody | |
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| pTau antibody | |
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| Tauopathy and respiratory failure, included antibody |
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靶标信息
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
产品来源
洱畔科技实验室
