Anti-PEA-15 (Phospho-Ser104) antibody
产品特性
| Product Cat#: | AB-07-3461 |
| Product type: | Primary antibody |
| Antigen: | PEA-15 |
| Immunogen: | A synthetic peptide derived from human PEA-15 around the phosphorylation site of serine 104(I-P-SP-A-K). The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:20000); Western Blot (1:500-1:2500); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Astrocytic phosphoprotein PEA-15; PE15; PEA15; PED; Phosphoprotein enriched in diabetes |
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靶标信息
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
产品来源
洱畔科技实验室
