Anti-PAK3 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PAK3 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600) |
| Reactivity: | Human, Monkey |
| Clonality (clone number): | Monoclonal(F11-G8) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Beta PAK antibody |
| bPAK antibody | |
| CDKN1A antibody | |
| hPAK3 antibody | |
| Mental retardation X linked 30 antibody | |
| MRX30 antibody | |
| MRX47 antibody | |
| Oligophrenin 3 antibody | |
| OPHN3 antibody | |
| p21 (CDKN1A) activated kinase 3 antibody | |
| p21 activated kinase 3 antibody | |
| p21 CDKN1A activated kinase 3 antibody | |
| P21 protein (Cdc42/Rac) activated kinase 3 antibody | |
| PAK-3 antibody | |
| PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 antibody | |
| PAK3beta antibody | |
| Pak65alpha antibody | |
| Pak65beta antibody | |
| Serine threonine protein kinase PAK 3 antibody | |
| Stk4 antibody |
靶标信息
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
产品来源
洱畔科技实验室
