Anti-PAG1 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PAG1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human PAG1 331-432/432 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2200) |
| Reactivity: | Human, Mouse, Rat, Dog, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CBP |
| Csk Binding Protein | |
| Csk-binding protein | |
| FLJ37858 | |
| MGC138364 | |
| PAG 1 | |
| PAG | |
| PAG1 | |
| PAG1_HUMAN | |
| Phosphoprotein associated with glycosphingolipid enriched microdomains 1 | |
| Phosphoprotein associated with glycosphingolipid enriched microdomains | |
| Phosphoprotein associated with glycosphingolipid microdomains 1 | |
| Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | |
| Protein Associated with Glycosphingolipid Enriched Microdomains |
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靶标信息
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
产品来源
洱畔科技实验室
