Anti-OTUD6B antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | OTUD6B |
| Immunogen: | KLH conjugated synthetic peptide derived from human OTUD6B 51-150/293 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Dog, Rabbit, Saccharomyces cerevisiae |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10mM Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin300. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CGI-77 |
| DUBA-5 | |
| DUBA5 | |
| OTU domain containing protein 6B | |
| OTU domain-containing protein 6B | |
| OTU6B_HUMAN |
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靶标信息
Isoform 1: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (PubMed:21267069, PubMed:27864334). May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation (PubMed:27864334). May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation (PubMed:27864334). May also play a role in proteasome assembly and function (PubMed:28343629).
产品来源
洱畔科技实验室