Anti-NR1I2 antibody
产品特性
| Product Cat#: | AB-06-3201 | |||||||||||||||||||||||||
| Product type: | Primary antibody | |||||||||||||||||||||||||
| Antigen: | NR1I2 | |||||||||||||||||||||||||
| Immunogen: | Recombinant protein | |||||||||||||||||||||||||
| Species immunized: | Mouse | |||||||||||||||||||||||||
| Isotype: | IgG2b | |||||||||||||||||||||||||
| Applications: | Western Blot (1:600-1:2000); Flow Cytometry (1:60-1:200); Immunocytochemistry (1:60-1:200) | |||||||||||||||||||||||||
| Reactivity: | Human | |||||||||||||||||||||||||
| Clonality (clone number): | Monoclonal (G1-D12) | |||||||||||||||||||||||||
| Form: | Liquid | |||||||||||||||||||||||||
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. | |||||||||||||||||||||||||
| Concentration: | 1 mg/ml | |||||||||||||||||||||||||
| Purity: | Protein A affinity purified | |||||||||||||||||||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | |||||||||||||||||||||||||
| Alternative names: | BXR antibody | Nr1i2 antibody | NR1I2_HUMAN antibody | Nuclear receptor subfamily 1 group I member 2 antibody | ONR 1 antibody | ONR1 antibody | Orphan nuclear receptor PAR 1 antibody | Orphan nuclear receptor PAR1 antibody | Orphan nuclear receptor PXR antibody | OTTHUMP00000215173 antibody | OTTHUMP00000215174 antibody | OTTHUMP00000215175 antibody | PAR 1 antibody | PAR 2 antibody | PAR antibody | PAR q antibody | PAR1 antibody | PAR2 antibody | PARq antibody | pregnane X nuclear receptor variant 2 antibody | Pregnane X receptor antibody | PRR antibody | PXR antibody | SAR antibody | Steroid and xenobiotic receptor antibody | SXR antibody |
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靶标信息
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
产品来源
洱畔科技实验室
