Anti-Neuropilin and Tolloid -like 1 antibody
产品特性
| Product Cat#: | AB-06-3106 |
| Product type: | Primary antibody |
| Antigen: | Neuropilin and tolloid -like 1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:2000-1:10000); Immunocytochemistry (1:100-1:400); Immunohistochemistry(1:100) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal(A3-D1) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AI851453 antibody |
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| Neuropilin and tolloid like 1 antibody |
靶标信息
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
产品来源
洱畔科技实验室
