Anti-NCR3 antibody
产品特性
| Product Cat#: | AB-07-4050 |
| Product type: | Primary antibody |
| Antigen: | NCR3 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from internal of human NCR3. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:40000) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Natural cytotoxicity triggering receptor 3 ,Natural killer cell p30-related protein; NKp30; NK-p30; Activating natural killer receptor p30; CD337 antigen |
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靶标信息
Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
产品来源
洱畔科技实验室
