Anti-Nanog antibody
产品特性
| Product Cat#: | AB-06-3044 |
| Product type: | Primary antibody |
| Antigen: | Nanog |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:400-1:1500 );Immunocytochemistry ( 1:50-1:200 )/ Immunofluorescence;Immunohistochemistry ( 1:100-1:150 );Immunoprecipitation ( 1:50 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS ( pH7.4 ), 1 %BSA, 40 %Glycerol. Preservative: 0.05 % Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | NANOG_MOUSE |
| Embryonic Stem Cell Specific Homeobox Protein (Nanog) | |
| ENK | |
| FLJ12581 | |
| FLJ40451 | |
| Homeobox Transcription Factor Nanog | |
| Nanog Homeobox | |
| Homeobox Protein NANOG | |
| ES cell-associated Protein 4 | |
| Early Embryo Specific Expression NK-type Homeobox Protein | |
| Homeobox Transcription Factor Nanog | |
| Nanog | |
| Ecat4. |
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靶标信息
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5′-TAAT[GT][GT]-3′ or 5′-[CG][GA][CG]C[GC]ATTAN[GC]-3′. When overexpressed, promotes cells to enter into S phase and proliferation.
产品来源
洱畔科技实验室
