Anti-MuRF1 antibody
产品特性
| Product Cat#: | AB-06-3005 |
| Product type: | Primary antibody |
| Antigen: | MuRF1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:100); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (B8-E1) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | E3 ubiquitin-protein ligase TRIM63 antibody |
| FLJ32380 antibody | |
| IRF antibody | |
| Iris RING finger protein antibody | |
| MURF 1 antibody | |
| MURF-1 antibody | |
| MuRF1 antibody | |
| MURF2 antibody | |
| Muscle specific ring finger protein 1 antibody | |
| Muscle specific ring finger protein 2 antibody | |
| Muscle-specific RING finger protein 1 antibody | |
| OTTHUMP00000008701 antibody | |
| RING finger protein 28 antibody | |
| RNF 28 antibody | |
| RNF28 antibody | |
| SMRZ antibody | |
| Striated muscle RING zinc finger protein antibody | |
| TRI63_HUMAN antibody | |
| TRIM 63 antibody | |
| Trim63 antibody | |
| Tripartite motif containing 63 antibody | |
| tripartite motif containing 63, E3 ubiquitin protein ligase antibody | |
| Tripartite motif containing protein 63 antibody | |
| Tripartite motif-containing protein 63 antibody | |
| Ubiquitin ligase TRIM63 antibody |
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靶标信息
E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
产品来源
洱畔科技实验室
