Anti-Methionine Aminopeptidase 2 antibody
产品特性
| Product Cat#: | AB-06-2869 |
| Product type: | Primary antibody |
| Antigen: | Methionine Aminopeptidase 2 |
| Immunogen: | Recombinant protein within C-terminal human Methionine Aminopeptidase 2 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:50-1:200); Flow Cytometry (1:50-1:100); Immunofluorescence (1:50-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JG39-79) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | A930035J23Rik antibody |
| AI047573 antibody | |
| AL024412 antibody | |
| Amp2 antibody | |
| AU014659, antibody | |
| EIF 2 associated p67 homolog antibody | |
| EIF-2-associated p67 antibody | |
| Initiation factor 2 associated 67 kDa glycoprotein antibody | |
| Initiation factor 2-associated 67 kDa glycoprotein antibody | |
| MAP 2 antibody | |
| MAP2 antibody | |
| MAP2_HUMAN antibody | |
| MetAP 2 antibody | |
| Metap2 antibody | |
| Methionine aminopeptidase 2 antibody | |
| Methionyl aminopeptidase 2 antibody | |
| MGC102452 antibody | |
| MGC127390 antibody | |
| MGC53792 antibody | |
| MNPEP antibody | |
| P67 antibody | |
| P67eIF2 antibody | |
| Peptidase M antibody | |
| Peptidase M2 antibody |
展开
靶标信息
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
产品来源
洱畔科技实验室
