Anti-MDR1 antibody
产品特性
| Product Cat#: | AB-06-2841 |
| Product type: | Primary antibody |
| Antigen: | MDR1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MDR1 21-100/1272 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1μg/Test) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | P-Glycoprotein |
| Multi Drug Resistance Associated Protein, ABCB1 | |
| ATP-binding cassette sub-family B (MDR/TAP), member 1 | |
| ABC20 | |
| CD243 | |
| CD243 antigen | |
| CLCS | |
| Multidrug resistance protein 1 | |
| P glycoprotein 1 | |
| p-GP | |
| gp170 | |
| P gp | |
| PGY1 |
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靶标信息
Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218).
产品来源
洱畔科技实验室