Anti-MED12 antibody
Specifications
| Product Cat#: | AB-07-0776 |
| Immunogen: | A synthetic peptide derived from human MED12. The exact amino-acid sequence is proprietary. |
| Antigen: | MED12 |
| Product type: | Primary antibody |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:20000); Immunohistochemistry (1:50~1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230;Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; OPA-containing protein; Trinucleotide repeat-containing gene 11 protein |
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靶标信息
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
产品来源
洱畔科技实验室
