Anti-MASP1/MASP3 antibody
产品特性
| Product Cat#: | AB-06-2809 |
| Product type: | Primary antibody |
| Antigen: | MASP1/MASP3 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MASP 20-120/699 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | MASP1/3 |
| MASP-1 | |
| Complement factor MASP-3 | |
| Complement factor MASP3 | |
| Complement-activating component of Ra-reactive factor | |
| CRARF | |
| EC 3.4.21 | |
| Mannan binding lectin serine protease 1 | |
| Mannose binding lectin associated serine protease 1 | |
| Mannose binding protein associated serine protease | |
| Mannose-binding lectin-associated serine protease 1 | |
| Mannose-binding lectin-associated serine protease-1 | |
| MASP | |
| PRSS 5 | |
| Ra reactive factor serine protease p100 | |
| Ra-reactive factor serine protease p100 | |
| RaRF | |
| Serine protease 5 | |
| MASP1_HUMAN. Mannan-binding lectin serine protease 1 | |
| Mannan-binding lectin serine protease 1 heavy chain |
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靶标信息
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development (PubMed:21258343).
产品来源
洱畔科技实验室
