Anti-MARK3 antibody
产品特性
| Product Cat#: | AB-06-2805 |
| Product type: | Primary antibody |
| Antigen: | MARK3 |
| Immunogen: | Recombinant protein within human Mark3 aa 600-750 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot(1:500); Immunoprecipitation(1:10-1:50); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:100-1:200); Immunocytochemistry (1:50-1:200); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JE44-84) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | C-TAK1 antibody |
| Cdc25C associated protein kinase 1 antibody | |
| Cdc25C-associated protein kinase 1 antibody | |
| cTAK1 antibody | |
| ELKL motif kinase 2 antibody | |
| EMK-2 antibody | |
| Emk2 antibody | |
| ETK 1 antibody | |
| KIAA4230 antibody | |
| KP78 antibody | |
| MAP microtubule affinity regulating kinase 3 antibody | |
| MAP/microtubule affinity-regulating kinase 3 antibody | |
| Mark3 antibody | |
| MARK3_HUMAN antibody | |
| Par 1a antibody | |
| PAR1A antibody | |
| Protein kinase STK10 antibody | |
| Ser/Thr protein kinase PAR-1 antibody | |
| Serine threonine protein kinase p78 antibody | |
| Serine/threonine-protein kinase p78 antibody |
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靶标信息
Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on ‘Ser-216’. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
产品来源
洱畔科技实验室
