Anti-KLHL24 antibody
产品特性
| Product Cat#: | AB-06-2630 |
| Product type: | Primary antibody |
| Antigen: | KLHL24 |
| Immunogen: | KLH conjugated synthetic peptide derived from human KLHL24 1-100/600 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | DRE1 |
| FLJ20059 | |
| FLJ25796 | |
| Kainate Receptor Interacting Protein for GluR6 | |
| Kelch Like 24 (Drosophila) | |
| Kelch Like Protein 24 | |
| KRIP6 | |
| OTTHUMP00000211002 | |
| OTTHUMP00000212605 | |
| Protein DRE1 |
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靶标信息
Necessary to maintain the balance between intermediate filament stability and degradation, a process that is essential for skin integrity (PubMed:27889062). As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14 and controls its levels during keratinocytes differentiation (PubMed:27798626). Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties (By similarity).
产品来源
洱畔科技实验室