Anti-KIBRA antibody
产品特性
| Product Cat#: | AB-06-2593 |
| Product type: | Primary antibody |
| Antigen: | KIBRA |
| Immunogen: | KLH conjugated synthetic peptide derived from human KIBRA 351-450/1113 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | HBeAg-Binding Protein 3 |
| HBEBP36 | |
| KIAA0869 | |
| KIBRA | |
| Kidney and Brain Protein | |
| Protein KIBRA | |
| Protein WWC1 | |
| WW and C2 Domain Containing 1 | |
| WW C2 and Coiled-Coil Domain Containing 1 | |
| WW Domain-Containing Protein 1 | |
| WWC1 | |
| KIBRA_HUMAN |
展开
靶标信息
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade.
产品来源
洱畔科技实验室
