购物车里没有产品

四星推荐产品

Anti-Ki67 Recombinant Rabbit Monoclonal antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-5013
Anti-Ki67 Recombinant Rabbit Monoclonal antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-5013
Product type: Primary antibody
Antigen: Ki67
Immunogen: Synthetic peptide within human Ki67.
Molecular weight: Predicted band size: 345-395 kDa;
Species immunized: Rabbit
Isotype: IgG
Applications: Immunohistochemistry-Paraffin (1:5000-1:10000); Immunocytochemistry (1:100-1:200); Immunofluorescence (1:250-1:500); Flow Cytometry (1:500-1:1000)
Reactivity: Human, Mouse, Rat
Clonality (clone number): Monoclonal, SR00-02
Form: Liquid
Buffer: 1*PBS buffer (pH7.4), 40% glycerol, 0.1% BSA, 0.05% NaN3.
Concentration: 1 mg/mL
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Antigen identified by monoclonal antibody Ki 67 antibody
Antigen identified by monoclonal antibody Ki-67 antibody
Antigen KI-67 antibody
Antigen KI67 antibody
Antigen Ki67 antibody
KI67_HUMAN antibody
KIA antibody
Marker of proliferation Ki-67 antibody
MIB 1 antibody
MIB antibody
MKI67 antibody
PPP1R105 antibody
Proliferation marker protein Ki-67 antibody
Proliferation related Ki 67 antigen antibody
Protein phosphatase 1 regulatory subunit 105 antibody
RP11-380J17.2 antibody
展开

靶标信息

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226).
Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226).
Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226).
Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551).
Does not contribute to the internal structure of mitotic chromosomes (By similarity).
May play a role in chromatin organization (PubMed:24867636).
It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable)

产品来源

洱畔科技实验室