Anti-KDM6B Rabbit Polyclonal Antibody
产品特性
| Product Cat#: | AB-06-5124 |
| Product type: | Primary antibody |
| Antigen: | Kdm6b |
| Immunogen: | Synthetic peptide between 1023-1057 amino acids of Mouse Kdm6b. |
| Molecular weight: | Predicted band size: 176.4 kDa |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 40% glycerol, 0.1% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Histone demethylase JMJD3 antibody |
| JmjC domain containing protein 3 antibody | |
| JmjC domain-containing protein 3 antibody | |
| Jumonji D3 antibody | |
| Jumonji domain containing 3 antibody | |
| Jumonji domain containing 3 histone lysine demethylase antibody | |
| Jumonji domain containing protein 3 antibody | |
| Jumonji domain-containing protein 3 antibody | |
| Kdm6b antibody | |
| KDM6B_HUMAN antibody | |
| KIAA0346 antibody | |
| Lysine demethylase 6B antibody | |
| Lysine K specific demethylase 6B antibody | |
| Lysine specific demethylase 6B antibody | |
| Lysine-specific demethylase 6B antibody |
靶标信息
Histone demethylase that specifically demethylates ‘Lys-27’ of histone H3, thereby playing a central role in histone code (PubMed:17713478, PubMed:17825402, PubMed:17851529, PubMed:18003914).
Demethylates trimethylated and dimethylated H3 ‘Lys-27’ (PubMed:17713478, PubMed:17825402, PubMed:17851529, PubMed:18003914).
Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529).
Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402).
Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity).
产品来源
洱畔科技实验室
