Anti-KDM3A antibody
产品特性
| Product Cat#: | AB-06-2569 |
| Product type: | Primary antibody |
| Antigen: | KDM3A |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1:100-1:200); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (C2-G10) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | DKFZp686A24246 antibody |
| DKFZp686P07111 antibody | |
| JHDM2A antibody | |
| JHMD2A antibody | |
| JmjC Domain-Containing Histone Demethylation Protein 2A antibody | |
| JMJD1 antibody | |
| JMJD1A antibody | |
| Jumonji C Domain Containing Histone Demethylase 2A antibody | |
| Jumonji Domain Containing 1 antibody | |
| Jumonji Domain Containing 1A antibody | |
| Jumonji Domain Containing Protein 1A antibody | |
| Jumonji Domain-Containing Protein 1A antibody | |
| Kdm3a antibody | |
| KDM3A_HUMAN antibody | |
| KIAA0742 antibody | |
| Lysine (K) Specific Demethylase 3A antibody | |
| Lysine-Specific Demethylase 3A antibody | |
| Testis Specific Protein A antibody | |
| TSGA antibody |
靶标信息
Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 ‘Lys-9’ residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 ‘Lys-9’. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 ‘Lys-9’ demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
产品来源
洱畔科技实验室
