Anti-Integrin linked ILK Antibody
产品特性
| Product Cat#: | AB-06-2482 |
| Product type: | Primary antibody |
| Antigen: | Integrin linked ILK |
| Immunogen: | Recombinant protein within Human Integrin linked ILK aa 1-290. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunocytochemistry (1:80-1:200); Immunohistochemistry (1:80-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 59 kDa serine/threonine protein kinase antibody |
| 59 kDa serine/threonine-protein kinase antibody | |
| DKFZp686F1765 antibody | |
| Epididymis secretory protein Li 28 antibody | |
| HEL S 28 antibody | |
| ILK 1 antibody | |
| ILK 2 antibody | |
| ILK antibody | |
| ILK-1 antibody | |
| ILK-2 antibody | |
| ILK_HUMAN antibody | |
| ILK1 antibody | |
| ILK2 antibody | |
| Integrin linked kinase 2 antibody | |
| Integrin linked Kinase antibody | |
| Integrin linked protein kinase antibody | |
| Integrin-linked protein kinase antibody | |
| p59 antibody | |
| p59ILK antibody |
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靶标信息
Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).
产品来源
洱畔科技实验室