Anti-IL1R1 antibody
产品特性
| Product Cat#: | AB-06-2403 |
| Product type: | Primary antibody |
| Antigen: | IL1R1 |
| Immunogen: | Purified recombinant fragment of human IL1R1 expressed in E. Coli |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:800-1:2000); Flow Cytometry (1:80-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (D12-D2) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Antigen CD121a antibody |
| CD121 antigen-like family member A antibody | |
| CD121a antibody | |
| CD121a antigen antibody | |
| D2S1473 antibody | |
| IL 1 antibody | |
| IL 1R 1 antibody | |
| IL 1R alpha antibody | |
| IL 1RT1 antibody | |
| IL-1R-1 antibody | |
| IL-1R-alpha antibody | |
| IL-1RT-1 antibody | |
| IL-1RT1 antibody | |
| IL1 inhibitor antibody | |
| IL1R antibody | |
| IL1R1 antibody | |
| IL1R1_HUMAN antibody | |
| IL1RA antibody | |
| IL1RN antibody | |
| IL1RT1 antibody | |
| Interleukin 1 receptor alpha type 1 antibody | |
| Interleukin 1 receptor antagonist protein (IRAP) antibody | |
| Interleukin 1 receptor type I antibody | |
| Interleukin receptor 1 antibody | |
| Interleukin-1 receptor alpha antibody | |
| Interleukin-1 receptor type 1 Interleukin-1 receptor type I antibody | |
| p80 antibody |
展开
靶标信息
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed:10653850).
产品来源
洱畔科技实验室
