Anti-IL-1R2 antibody
产品特性
| Product Cat#: | AB-06-2404 |
| Product type: | Primary antibody |
| Antigen: | IL-1R2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human IL-1R II 301-398/398 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:300-1:800); Flow Cytometry (1-2μg/test) |
| Reactivity: | Mouse, Rat, Dog and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | IL1 Receptor II |
| IL-1R II | |
| IL1 Receptor 2 | |
| interleukin-1 receptor type 2 precursor | |
| IL1R2 | |
| CD121b | |
| IL1RB | |
| CD121 | |
| CD121 antigen-like family member B | |
| CD121b | |
| CD121B Antigen | |
| CDW121B | |
| IL-1R-2 | |
| IL-1R-beta | |
| IL-1R2 | |
| IL-1RT-2 | |
| IL-1RT2 | |
| IL1R Beta | |
| Il1r-2 | |
| IL1R2 | |
| IL1RB | |
| Interleukin 1 receptor, beta, type II | |
| Interleukin 1 receptor, type II | |
| Interleukin-1 receptor beta | |
| Interleukin-1 receptor type 2 | |
| MGC137383 | |
| MGC47725 | |
| p68 | |
| IL1 Receptor II | |
| IL1R2_HUMAN. |
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靶标信息
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
产品来源
洱畔科技实验室
